This webinar on the topic “Complement in the Brain” is organized by the International Complement Society. Speakers will explore the essential role of the complement system in brain health and disease. In  diverse neurological disorders, including Alzheimer's disease and other dementias, demyelinating diseases, stroke, brain injury, multiple sclerosis and schizophrenia, complement activation is intricately involved in driving neuroinflammatory processes that contribute to disease progression. Leading experts will discuss cutting-edge research that uncovers how complement proteins modulate neural plasticity in development and mediate neurodegeneration in disease. The webinar will highlight the dual role of complement in both protecting the brain and promoting neuroinflammation; these insights help identify potential therapeutic targets. Attendees will learn how complement drives neuropathology and how complement-targeting therapies can be used to stop or slow the progression of neurodegenerative diseases. Through these discussions, the event will aim to foster understanding of the roles of complement in brain health and disease and how targeting complement offers novel approaches to combat brain inflammation, ultimately improving patient care and outcomes.

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